iPSCs from Diverse Species

iPSCs from Diverse Species PDF Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0323851851
Category : Science
Languages : en
Pages : 274

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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology Covers iPCSs from the following species: humans, monkeys, horses, dogs, pigs, rats, rabbits, and more Consists of contributions from stem cell leaders around the world

iPSCs from Diverse Species

iPSCs from Diverse Species PDF Author: Alexander Birbrair
Publisher: Academic Press
ISBN: 0323851851
Category : Science
Languages : en
Pages : 274

Get Book

Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology Covers iPCSs from the following species: humans, monkeys, horses, dogs, pigs, rats, rabbits, and more Consists of contributions from stem cell leaders around the world

Current Progress in IPSC-derived Cell Types

Current Progress in IPSC-derived Cell Types PDF Author: Alexander Birbrair
Publisher: Elsevier
ISBN: 0128238844
Category : Science
Languages : en
Pages : 336

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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells can be differentiated into different cell types. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how research of induced pluripotent stem cells can be reprogrammed to develop new treatment technologies in regenerative medicine. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived cardiomyocytes, skeletal muscles, brown adipocytes, airway epithelial cells, and much more Contributed by world-renown experts in the field

IPSCs in Tissue Engineering

IPSCs in Tissue Engineering PDF Author: Alexander Birbrair
Publisher: Elsevier
ISBN: 0128238097
Category : Science
Languages : en
Pages : 430

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Book Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how induced pluripotent stem cells (iPSCs) are being used to advance tissue engineering. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This book will address the advances in research of how iPSCs are being used for the generation of different tissues and organs such as the lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and tissue engineering and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics Covers the engineering of the following organs: lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and more Is contributed from stem cell leaders around the world

The International after 150 Years

The International after 150 Years PDF Author: George Comninel
Publisher: Routledge
ISBN: 1317487966
Category : Political Science
Languages : en
Pages : 279

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Book Description
The International Workingmen’s Association was the prototype of all organizations of the Labour movement and the 150th anniversary of its birth (1864-2014) offers an important opportunity to rediscover its history and learn from its legacy. The International helped workers to grasp that the emancipation of labour could not be won in a single country but was a global objective. It also spread an awareness in their ranks that they had to achieve the goal themselves, through their own capacity for organization, rather than by delegating it to some other force; and that it was essential to overcome the capitalist system itself, since improvements within it, though necessary to pursue, would not eliminate exploitation and social injustice. This book reconsider the main issues broached or advanced by the International – such as labor rights, critiques of capitalism and the search for international solidarity – in light of present-day concerns. With the recent crisis of capitalism, that has sharpened more than before the division between capital and labour, the political legacy of the organization founded in London in 1864 has regained profound relevance, and its lessons are today more timely than ever. This book was published as a special issue of Socialism and Democracy.

Human Embryonic Stem Cells

Human Embryonic Stem Cells PDF Author: Arlene Chiu
Publisher: Springer Science & Business Media
ISBN: 1592594239
Category : Science
Languages : en
Pages : 455

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Book Description
A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309471192
Category : Science
Languages : en
Pages : 139

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Book Description
Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.

Stem Cells in Reproductive Medicine

Stem Cells in Reproductive Medicine PDF Author: Carlos Simón
Publisher: Cambridge University Press
ISBN: 1107034477
Category : Medical
Languages : en
Pages : 199

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Book Description
Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.

Reproductive Sciences in Animal Conservation

Reproductive Sciences in Animal Conservation PDF Author: William V. Holt
Publisher: Springer
ISBN: 9781493908196
Category : Science
Languages : en
Pages : 0

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Book Description
Reproductive biology is more than the development of techniques for helping with too little or too much breeding. While some of the relevant techniques are useful for individual species, technical developments have to be backed up by thorough biological understanding of the background behind the problems. This book is therefore threefold; (1) it provides a snapshot of the state of the art in terms of species-specific reproductive technologies, whether for individual animals or whole taxonomic groups; (2) it sets the reproductive problems in context and emphasizes the links between animal-based problems and the wider world, e.g. reproductive fitness and (3) it looks forward and presents realistic assessments of how effective some of the more recently developed techniques in reproductive technology might be at combating extinctions. This is a wide-ranging book that will be relevant to anyone involved in reproductive biology or in species conservation and provides provide them some useful perspectives about the real utility of current and emerging technologies. It has contributions from experts in reproduction and related fields.

Principles of Cloning

Principles of Cloning PDF Author: Jose Cibelli
Publisher: Academic Press
ISBN: 0123865425
Category : Science
Languages : en
Pages : 572

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Book Description
Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. First and most comprehensive book on animal cloning, 100% revised Describes an in-depth analysis of current limitations of the technology and research areas to explore Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Conservation Genetics in the Age of Genomics

Conservation Genetics in the Age of Genomics PDF Author: George Amato
Publisher: Columbia University Press
ISBN: 0231502311
Category : Science
Languages : en
Pages : 504

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Book Description
Genome sequencing enables scientists to study genes over time and to test the genetic variability of any form of life, from bacteria to mammals. Thanks to advances in molecular genetics, scientists can now determine an animal's degree of inbreeding or compare genetic variation of a captive species to wild or natural populations. Mapping an organism's genetic makeup recasts such terms as biodiversity and species and enables the conservation of rare or threatened species, populations, and genes. By introducing a new paradigm for studying and preserving life at a variety of levels, genomics offers solutions to previously intractable problems in understanding the biology of complex organisms and creates new tools for preserving the patterns and processes of life on this planet. Featuring a number of high-profile researchers, this volume introduces the use of molecular genetics in conservation biology and provides a historical perspective on the opportunities and challenges presented by new technologies. It discusses zoo-, museum-, and herbarium-based biological collections, which have expanded over the past decade, and covers the promises and problems of genomic and reproductive technology. The collection concludes with the philosophical and legal issues of conservation genetics and their potential effects on public policy.