From One Cell: A Journey into Life's Origins and the Future of Medicine

From One Cell: A Journey into Life's Origins and the Future of Medicine PDF Author: Ben Stanger
Publisher: W. W. Norton & Company
ISBN: 1324005432
Category : Science
Languages : en
Pages : 447

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Book Description
Inside the quest to unlock the mysteries of development—and find the key to transforming our future. Each of us began life as a single cell. From this humble origin, we embarked on a risky journey fraught with opportunities for disaster. Yet, amazingly, we reached our destination intact, emerging as dazzlingly complex, exquisitely engineered assemblages of trillions of cells. This metamorphosis constitutes one of nature’s most spectacular yet commonplace magic tricks—and one of its most coveted secrets. In From One Cell, physician and researcher Ben Stanger offers a breathtaking glimpse into what scientists are discovering about how life and the body take shape, and how these revelations stand to revolutionize medicine and the future of human health. In vivid prose, Stanger leads readers on a gripping odyssey retracing this universal, yet unremembered, rite of passage. Through the eyes of the scientists unraveling development’s riddles in experiments as painstaking as they are inventive, we confront fascinating puzzles: how does the plethora of different tissues that compose our bodies arise from a single source? How do cells know what they are meant to become—skin or bone, blood or muscle—when all carry the same set of genetic instructions? Once a cell starts developing down one path, can it change its mind, or is its destiny irrevocably sealed? As Stanger shows us, the answers to these questions may at last empower us to solve some of our most persistently confounding medical challenges, from cancer to cognitive decline to degenerative disease. Recognizing tumors as evil doppelgangers of the embryo points the way toward new, more targeted cancer therapies. Learning how cells choose their identities and find their way in space could unlock lifesaving breakthroughs in regenerative medicine. The possibilities are extraordinary. Popular science at its best, From One Cell celebrates the power and beauty of understanding our collective beginnings.

The Dance of Life

The Dance of Life PDF Author: Magdalena Zernicka-Goetz
Publisher: Random House
ISBN: 0753552949
Category : Science
Languages : en
Pages : 268

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Book Description
'Quite simply the best book about science and life that I have ever read' - Alice Roberts How does life begin? What drives a newly fertilized egg to keep dividing and growing until it becomes 40 trillion cells, a greater number than stars in the galaxy? How do these cells know how to make a human, from lips to heart to toes? How does your body build itself? Magdalena Zernicka-Goetz was pregnant at 42 when a routine genetic test came back with that dreaded word: abnormal. A quarter of sampled cells contained abnormalities and she was warned her baby had an increased risk of being miscarried or born with birth defects. Six months later she gave birth to a healthy baby boy and her research on mice embryos went on to prove that – as she had suspected – the embryo has an amazing and previously unknown ability to correct abnormal cells at an early stage of its development. The Dance of Life will take you inside the incredible world of life just as it begins and reveal the wonder of the earliest and most profound moments in how we become human. Through Magda’s trailblazing research as a professor at Cambridge – where she has doubled the survival time of human embryos in the laboratory, and made the first artificial embryo-like structures from stem cells – you’ll discover how early life is programmed to repair and organise itself, what this means for the future of pregnancy, and how we might one day solve IVF disorders, prevent miscarriages and learn more about the dance of life as it starts to take shape. The Dance of Life is a moving celebration of the balletic beauty of life’s beginnings.

In Search of Cell History

In Search of Cell History PDF Author: Franklin M. Harold
Publisher: University of Chicago Press
ISBN: 022617431X
Category : Science
Languages : en
Pages : 318

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Book Description
This comprehensive history of cell evolution “deftly discusses the definition of life” as well as cellular organization, classification and more (San Francisco Book Review). The origin of cells remains one of the most fundamental mysteries in biology, one that has spawned a large body of research and debate over the past two decades. With In Search of Cell History, Franklin M. Harold offers a comprehensive, impartial take on that research and the controversies that keep the field in turmoil. Written in accessible language and complemented by a glossary for easy reference, this book examines the relationship between cells and genes; the central role of bioenergetics in the origin of life; the status of the universal tree of life with its three stems and viral outliers; and the controversies surrounding the last universal common ancestor. Harold also discusses the evolution of cellular organization, the origin of complex cells, and the incorporation of symbiotic organelles. In Search of Cell History shows us just how far we have come in understanding cell evolution—and the evolution of life in general—and how far we still have to go. “Wonderful…A loving distillation of connections within the incredible diversity of life in the biosphere, framing one of biology’s most important remaining questions: how did life begin?”—Nature

The Secret Language of Cells

The Secret Language of Cells PDF Author: Jon Lieff
Publisher: BenBella Books
ISBN: 1948836335
Category : Science
Languages : en
Pages : 325

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Book Description
Your cells are talking about you. Right now, both your inner and outer worlds are abuzz with chatter among living cells of every possible kind—from those in your body and brain to those in the environment around you. From electrical alerts to chemical codes, the greatest secret of modern biology, hiding in plain sight, is that all of life's activity boils down to one thing: conversation. While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer. He explains the surprising science of how very different cells—bacteria and brain cells, blood cells and viruses—all speak the same language. This overarching principle has been long overlooked because scientific journals use impenetrable jargon that makes it hard to be understood across disciplines, much less by the general public. Lieff presents a fascinating and accessible look into cellular communication science—a groundbreaking and comprehensive exploration of this biological phenomenon. In these pages, discover the intriguing lives of cells as they ask questions, get answers, give feedback, gather information, call for each other, and make complex decisions. During infections, immune T-cells tell brain cells that we should "feel sick" and lie down. Cancer cells warn their community about immune and microbe attacks. Gut cells talk with microbes to determine which are friends and which are enemies, and microbes talk with each other and with much more complicated human cells in ways that determine which medicines work and which will fail. With applications for immunity, chronic pain, weight loss, depression, cancer treatment, and virtually every aspect of health and biology, cellular communication is revolutionizing our understanding not just of disease, but of life itself. The Secret Language of Cells is required reading for anyone interested in following the conversation.

The Cell

The Cell PDF Author: Joshua Z. Rappoport
Publisher: National Geographic Books
ISBN: 1942952961
Category : Medical
Languages : en
Pages : 0

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Book Description
Your body has trillions of cells, and each one has the complexity and dynamism of a city. Your life, your thoughts, your diseases, and your health are all the function of cells. But what do you really know about what goes on inside you? The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant. The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world. Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover: A deeper understanding of how cells work and the basic nature of life on earth. Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research. The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells. The ability to make better decisions about health and to debunk the misinformation that comes in daily via media. Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.

The Cell

The Cell PDF Author: Joshua Z. Rappoport
Publisher: BenBella Books, Inc.
ISBN: 1944648976
Category : Medical
Languages : en
Pages : 272

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Book Description
Your body has trillions of cells, and each one has the complexity and dynamism of a city. Your life, your thoughts, your diseases, and your health are all the function of cells. But what do you really know about what goes on inside you? The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant. The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world. Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover: A deeper understanding of how cells work and the basic nature of life on earth. Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research. The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells. The ability to make better decisions about health and to debunk the misinformation that comes in daily via media. Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.

Unique Philosophy Book- Cosmocellular-Hypothesis: A Journey from Meditation to Modern-Medicine (Volume-1-C)

Unique Philosophy Book- Cosmocellular-Hypothesis: A Journey from Meditation to Modern-Medicine (Volume-1-C) PDF Author: Dr. Kamlesh N Patel
Publisher: Dhruv Publication (Self Publication)
ISBN: 9356029067
Category : Philosophy
Languages : en
Pages : 614

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Book Description
Welcome to still-unwritten-phenomena showing Nonmolecularly-Molecular Cosmocellular-World. Read a special & unique book (Cosmocellular-Hypothesis). No one would have ever read it before. This same Cosmocellular-Message you had read before 30 billion years, and will also read after 30 billion years,.....How it's possible according to universal Ancient-Vedic-Law of the Time-Replication & Thermodynamics-Laws of the Modern-Science (Waves-physics)? Indeed, all kind of the plant-kingdoms & animal-kingdoms on the earth, had reproduced , are reproducing & will reproduce from their same species only. Thus, our ancestors were not apes, but they were same as we look today. ..... How according to such joint-theory of cosmocellular-ancestory (and waves- &-particles-physics) as well as cytocosmic-ancestory, ---- can trace back us to Vedic-belief or philosophical-belief (which strongly prevailed before Charles Darwin) about the evolution of life on the earth that each living-species evolved separately & that none had changed their forms? That means, how a man evolved from a man only ,not from the ape or other species. In other words, man has descended from man only , & rat from rat only; similarly a banyan tree from banyan-tree only, & mango-tree from mango-tree only etc.etc. ? In short, a babool or banyan tree never never gives mango-fruit. ....... www.cosmocellular.com

The Immortal Life of Henrietta Lacks

The Immortal Life of Henrietta Lacks PDF Author: Rebecca Skloot
Publisher: Crown
ISBN: 0307589382
Category : Science
Languages : en
Pages : 386

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Book Description
#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

The Secret Language of Cells

The Secret Language of Cells PDF Author: Jon Lieff
Publisher: BenBella Books
ISBN: 1948836335
Category : Science
Languages : en
Pages : 325

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Book Description
Your cells are talking about you. Right now, both your inner and outer worlds are abuzz with chatter among living cells of every possible kind—from those in your body and brain to those in the environment around you. From electrical alerts to chemical codes, the greatest secret of modern biology, hiding in plain sight, is that all of life's activity boils down to one thing: conversation. While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer. He explains the surprising science of how very different cells—bacteria and brain cells, blood cells and viruses—all speak the same language. This overarching principle has been long overlooked because scientific journals use impenetrable jargon that makes it hard to be understood across disciplines, much less by the general public. Lieff presents a fascinating and accessible look into cellular communication science—a groundbreaking and comprehensive exploration of this biological phenomenon. In these pages, discover the intriguing lives of cells as they ask questions, get answers, give feedback, gather information, call for each other, and make complex decisions. During infections, immune T-cells tell brain cells that we should "feel sick" and lie down. Cancer cells warn their community about immune and microbe attacks. Gut cells talk with microbes to determine which are friends and which are enemies, and microbes talk with each other and with much more complicated human cells in ways that determine which medicines work and which will fail. With applications for immunity, chronic pain, weight loss, depression, cancer treatment, and virtually every aspect of health and biology, cellular communication is revolutionizing our understanding not just of disease, but of life itself. The Secret Language of Cells is required reading for anyone interested in following the conversation.

The Song of the Cell

The Song of the Cell PDF Author: Siddhartha Mukherjee
Publisher: Penguin Random House India Private Limited
ISBN: 9354927580
Category : Science
Languages : en
Pages : 552

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Book Description
From Pulitzer Prize-winning and #1 New York Times bestselling author of The Emperor of All Maladies and The Gene, The Song of The Cell is the third book in this extraordinary writer's exploration of what it means to be human-rich with Siddhartha Mukherjee's revelatory and exhilarating stories of scientists, doctors, and all the patients whose lives may be saved by their work. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves-hearts, blood, brains-are built from these compartments. Hooke christens them 'cells'. The discovery of cells-and the reframing of the human body as a cellular ecosystem-announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's, dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID-all could be viewed as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces readers with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, doctor, and prolific reader, The Song of the Cell is both panoramic and intimate-a masterpiece.