Author:
Publisher: Academic Press
ISBN: 9780080956961
Category : Science
Languages : en
Pages : 350
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Book Description
The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokine structure and function, as well as signaling, and its companion volume (Methods in Enzymology volume 461, focusing on chemokines as potential targets for disease intervention) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area. Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy Gathers tried, tested, and trusted methods and techniques from top players in chemokine research Provides an essential reference for researchers in the field
Author: Robert Repino
Publisher: Soho Press
ISBN: 1616956879
Category : Fiction
Languages : en
Pages : 400
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Book Description
With the fragile interspecies peace that followed the War With No Name under assault from land and sea, Sheba and Mort(e) have no choice but to take up their arms and enter once again into the conflict that threatened to tear them apart. “Repino's dog, cat, and beaver soldiers are nakedly real, as honest as any characters in modern fiction. As horrible as it may sound, may The War With No Name never end." —Corey Redekop, author of Husk In the aftermath of the War With No Name, the Colony has been defeated, its queen lies dead, and the world left behind will never be the same. In her madness, the queen used a strange technology to uplift the surface animals, turning dogs and cats, bats and bears, pigs and wolves into intelligent, highly evolved creatures who rise up and kill their oppressors. And now, after years of bloodshed, these sentient beasts must learn to live alongside their sworn enemies—humans. Far removed from this newly emerging civilization, a housecat turned war hero named Mort(e) lives a quiet life with the love he thought he had lost, a dog named Sheba. But before long, the chaos that they escaped comes crashing in around them. An unstoppable monster terrorizes a nearby settlement of beavers. A serial killer runs amok in the holy city of Hosanna. An apocalyptic cult threatens the fragile peace. And a mysterious race of amphibious creatures rises from the seas, intent on fulfilling the Colony’s destiny and ridding the world of all humans. No longer able to run away, Sheba and Mort(e) rush headlong into the conflict, ready to fight but unprepared for a world that seems hell-bent on tearing them apart. In the twilight of all life on Earth, love survives, but at a cost that only the desperate and the reckless are willing to pay.
Author: Amy M. Fulton
Publisher: Springer Science & Business Media
ISBN: 1603272674
Category : Medical
Languages : en
Pages : 181
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Book Description
Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that chemokine receptors are also expressed by many other cells including endothelial and epithelial cells. Since the first description of chemokine receptors on malignant cells in 2001, an extensive literature has developed describing the expression and function of chemokine receptors in many malignancies. These studies support the initial hypothesis that malignant cells use chemokine receptors to migrate to distant sites of ligand expression and that expression of certain receptors is associated with a poor prognosis. It has also become apparent that malignancies of different tissues may use a diverse profile of chemokine receptors and that the same receptor may mediate metastasis to different sites in tumors of different histological origins. Receptor function may also maintain survival and expansion of the primary tumor.
Author: Nathalie Quintane
Publisher: La Presse
ISBN: 9781934200711
Category : Literary Criticism
Languages : en
Pages : 0
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Book Description
Nathalie Quintane circumvents the biographical to explore this well-known story from inside Joan's experience.
Author: Bianca D' Arc
Publisher: Kensington Publishing Corp.
ISBN: 0758272421
Category : Fiction
Languages : en
Pages : 304
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Book Description
Sizzling attraction meets unstoppable adventure in Bianca D'Arc's captivating new paranormal romance. . . For Emily Parkington, the thrill of flying charter planes for Praxis Air has lately been tinged with dread. Mysterious cargo flights and a high number of fatal crashes lead Emily to suspect something sinister behind the scenes. And if her new colleague is involved, Emily won't hesitate to turn him in, in spite of Sam Archer's sexy charm and irresistibly easy confidence. Enemy or potential ally? Sam can't be sure of anything where Emily is concerned, except how much he wants her. Immune to the zombie virus created through military research, Sam is working undercover to find out if Praxis is trafficking forbidden technology. It was a potentially deadly assignment even before he found himself distracted by a woman he scarcely knows. And when a "controlled" experiment goes horribly wrong, there will be no limit to the danger they both face. . .or how far he's willing to go to save her. . . Praise for Bianca D'Arc "D'Arc delivers a creepy and pulse-pounding story of danger." -Romantic Times on Half Past Dead "D'Arc's stories are a pleasure to read." -Romantic Times
Author: United States. Congress. House. Committee on Government Operations. Government Activities and Transportation Subcommittee
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 530
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Book Description
Author: Mrs. Oliphant (Margaret)
Publisher:
ISBN:
Category : France
Languages : en
Pages : 448
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Book Description
Author: Alfred Seabold Eli Ackermann
Publisher:
ISBN:
Category : Common fallacies
Languages : en
Pages : 1006
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Book Description
Author: Ralph Augustus Roberts
Publisher:
ISBN:
Category : Calculus, Integral
Languages : en
Pages : 400
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Book Description
Author: Lili Wilkinson
Publisher:
ISBN: 1921167009
Category : Christian saints
Languages : en
Pages : 182
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Book Description
Joan of Arc left home when she was fifteen. At sixteen she led the French army to victory. At nineteen she was burned to death at the stake. Angel or witch? Saint or heretic? Messenger from God or crazy teenager? Who was Joan of Arc? A true coming of age story about one of the most intriguing women in history.
