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Author: Margi Sheth
Publisher: Academic Press
ISBN: 0128023686
Category : Science
Languages : en
Pages : 142
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Book Description
Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaborators Describes lessons learned through TCGA to prepare for potential roadblocks Evaluates policy considerations that are needed to avoid pitfalls Recommends strategies to make project management more efficient
Author: Margi Sheth
Publisher: Academic Press
ISBN: 0128023686
Category : Science
Languages : en
Pages : 142
Get Book
Book Description
Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaborators Describes lessons learned through TCGA to prepare for potential roadblocks Evaluates policy considerations that are needed to avoid pitfalls Recommends strategies to make project management more efficient
Author: Dr. Spineanu Eugenia
Publisher: Dr. Spineanu Eugenia
ISBN:
Category : Medical
Languages : en
Pages : 362
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Book Description
Are you or a loved one facing the challenges of thymic tumors? Discover hope, empowerment, and expert guidance in "Thymic Tumors Unveiled: A Comprehensive Guide to Diagnosis, Treatment, and Hope." This comprehensive treatise offers a lifeline to those navigating the rare and complex world of thymic tumors. From understanding the disease's origins, anatomy, and genetic factors to exploring cutting-edge treatments and the latest in precision medicine, this book covers it all. Inside, you'll find: In-Depth Knowledge: Dive into the intricacies of thymic tumors, from their historical perspective to the latest research breakthroughs. Understand the anatomy of the thymus gland, the role of genetics, and the influence of environmental factors. Cutting-Edge Therapies: Explore the future of thymic tumor treatment with precision medicine, immunotherapies, and targeted therapies. Learn how advancements in molecular diagnostics are reshaping the landscape of care. Patient-Centered Care: Discover how patient advocacy groups and support networks offer invaluable resources, emotional support, and insights to navigate the thymic tumor journey. Global Access to Care: Learn about the vision for equitable access to thymic tumor care, breaking down geographical barriers and promoting international collaboration. Data-Driven Insights: Explore the role of data-driven decision-making, predictive analytics, and real-world evidence in shaping the future of thymic tumor management. "Thymic Tumors Unveiled" is more than a book; it's a beacon of hope for patients and their families. With clear and accessible language, this treatise empowers you to become an informed advocate for your health, guiding you towards better outcomes and improved quality of life. Join the global movement towards a brighter future for thymic tumor patients. Whether you're a healthcare professional, a patient, or a caregiver, this treatise offers essential knowledge, inspiration, and a vision for a world where thymic tumors are better understood, treated, and ultimately conquered.
Author: Susan L. Speaker
Publisher: Chemical Heritage Foundation
ISBN: 9780941901109
Category : Science
Languages : en
Pages : 44
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Book Description
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.
Author: Dan J. Stein
Publisher: Academic Press
ISBN: 0128150637
Category : Psychology
Languages : en
Pages : 310
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Book Description
Global Mental Health and Neuroethics explores conceptual, ethical and clinical issues that have emerged with the expansion of clinical neuroscience into middle- and low-income countries. Conceptual issues covered include avoiding scientism and skepticism in global mental health, integrating evidence-based and value-based global medicine, and developing a welfarist approach to the practice of global psychiatry. Ethical issues addressed include those raised by developments in neurogenetics, cosmetic psychopharmacology and deep brain stimulation. Perspectives drawing on global mental health and neuroethics are used to explore a number of different clinical disorders and developmental stages, ranging from childhood through to old age. Synthesizes existing work at the intersection of global mental health and neuroethics Presents the work of leading practitioners of global mental health and neuroethics who address clinical issues Looks at clinical decision-making in settings with non-Western values and customs Covers patient empowerment, human rights, cognitive enhancement, and more
Author: VIRUTI SHIVAN
Publisher: Viruti Satyan Shivan
ISBN:
Category : Science
Languages : en
Pages : 221
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Book Description
Dive into the groundbreaking realm of bioinformatics with "Bioinformatics Scientist- The Comprehensive Guide," your ultimate resource for mastering the intricacies of biological data analysis. This guide demystifies the complex world of genetic codes, protein databases, and computational biology, providing an unparalleled journey into the heart of modern biology. Without the need for images or illustrations, the book focuses purely on the rich, detailed narrative and insightful analyses, ensuring an engaging and immersive reading experience. Whether you're a budding scientist, a seasoned researcher, or simply a curious mind, this book promises to transform your understanding of biology, offering a fresh perspective on how data can unlock the mysteries of life itself. In an era where information is abundant yet clarity is scarce, this comprehensive guide stands out by not only covering the technical aspects of bioinformatics but also by connecting the dots between computational techniques and their real-world applications in solving biological problems. Through vivid hypothetical scenarios and personal anecdotes from experts in the field, readers are taken on a captivating journey from the basics of DNA sequencing to the forefront of genetic research. The book emphasizes the critical role of bioinformatics in advancing healthcare, environmental conservation, and our understanding of evolution, making it an essential addition to the library of anyone looking to make a mark in the biological sciences.
Author: Saif Aldeen Saleh AlRyalat
Publisher: CRC Press
ISBN: 0429667671
Category : Computers
Languages : en
Pages : 110
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Book Description
Open Access Data is emerging as a source for cutting edge scholarship. This concise book provides guidance from generating a research idea to publishing results. Both young researchers and well-established scholars can use this book to upgrade their skills with respect to emerging data sources, analysis, and even post-publishing promotion. At the end of each chapter, a tutorial simulates a real example, allowing readers to apply what they learned about accessing open data, and analyzing this data to reach the results. This book can be of use by established researchers analyzing data, publishing, and actively promoting ongoing and research. Key selling features: Describes the steps, from A-Z, for doing open data research Includes interactive tutorials following each chapter Provides guidelines for readers so that they can use their own accessed open data Reviews recent software and websites promoting and enabling open data research Supplements websites which update recent open data sources
Author: Dr. Spineanu Eugenia
Publisher: Dr. Spineanu Eugenia
ISBN:
Category : Cooking
Languages : en
Pages : 243
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Book Description
"Diabetes Unveiled: A Comprehensive Guide to Understanding, Management, and Future Directions" is an exhaustive exploration into the multifaceted world of diabetes, a condition that affects millions globally. This treatise delves deep into the biological underpinnings of the disease, from the intricacies of pancreatic function to the complexities of hormonal regulation. It sheds light on the symptoms, diagnostic criteria, and the various stages of diabetes, providing invaluable insights for both patients and healthcare professionals. The guide also discusses the myriad complications associated with diabetes, from microvascular to neuropathic issues, offering a holistic view of the challenges faced by those with the condition. Beyond the medical aspects, this work delves into the socio-cultural and economic dimensions of diabetes, addressing the disparities in healthcare access, the influence of cultural beliefs on health behaviors, and the economic burden of the disease on societies. It emphasizes the importance of patient narratives, community-based interventions, and the role of schools and workplaces in managing and preventing diabetes. In its concluding sections, the treatise looks to the future, discussing the latest in technological advancements, the potential of stem cell research, and the emerging role of artificial intelligence in diabetes care. It also touches upon the ethical considerations in diabetes research, ensuring a well-rounded understanding of the subject. "Diabetes Unveiled" stands as a testament to the ever-evolving understanding of diabetes, serving as an essential resource for all stakeholders in the fight against this global health challenge.
Author: Ali S. Faqi
Publisher: Academic Press
ISBN: 0123878152
Category : Business & Economics
Languages : en
Pages : 904
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Book Description
A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --
Author:
Publisher: Richards Education
ISBN:
Category : Family & Relationships
Languages : en
Pages : 144
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Book Description
Navigating the complexities of Marfan Syndrome can be challenging, but with the right information, support, and guidance, individuals and families affected by this condition can lead fulfilling lives. "Understanding Marfan Syndrome: A Complete Guide" offers a comprehensive look into every aspect of Marfan Syndrome, providing essential knowledge from genetic foundations to daily management strategies. Crafted by experts in the field, this guide breaks down the medical, psychological, and social nuances of Marfan Syndrome. It begins with a detailed exploration of what Marfan Syndrome is, including its genetic origins, symptoms, and diagnostic criteria. It then delves into the intricacies of medical management, addressing vital concerns such as cardiovascular health, eye care, and the specifics of surgical options. Beyond medical advice, the book offers practical tips for daily living, legal advocacy, and navigating emotional and psychological impacts. Each chapter is meticulously structured to ensure that readers—whether they are patients, family members, educators, or healthcare providers—find valuable, actionable information. The book also highlights the latest advancements in research and provides a wealth of resources and support networks. "Understanding Marfan Syndrome: A Complete Guide" is more than just a medical manual; it is a companion for anyone touched by Marfan Syndrome, offering hope and empowering readers with knowledge to tackle the challenges and embrace the opportunities of living with Marfan Syndrome.
Author: Geraldine A. Van der Auwera
Publisher: O'Reilly Media
ISBN: 1491975164
Category : Computers
Languages : en
Pages : 496
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Book Description
Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytes—or over 50 million gigabytes—of genomic data, and they’re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian O’Connor of the UC Santa Cruz Genomics Institute, guide you through the process. You’ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra
