Coalescent

Coalescent PDF Author: Stephen Baxter
Publisher: Del Rey
ISBN: 0345457862
Category : Fiction
Languages : en
Pages : 546

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Book Description
“Lean, taut storytelling . . . breakneck stuff . . . Arguably his most accessible book to date—Baxter [is] resplendent.”—SFX magazine When his father dies suddenly, George Poole stumbles onto a family secret: He has a twin sister he never knew existed, who was raised by an enigmatic cult called the Order. The Order is a hive—a human hive with a dominant queen—that has prospered below the streets of Rome for almost two millennia. After Poole enters the Order’s vast underground city and meets the disturbing inhabitants, he uncovers evidence that they have embarked on a divergent evolutionary path. These genetically superior humans are equipped with the tools necessary to render modern Homo sapiens as extinct as the Neanderthals. And now they are preparing to leave their underground realm. “[Excels] at both action-packed storytelling and philosophical speculation.”—Library Journal “Utterly fascinating . . . constantly surprising . . . Coalescent reveals a new side to Baxter’s vast talent.”—Locus

Coalescent

Coalescent PDF Author: Stephen Baxter
Publisher: Del Rey
ISBN: 0345457862
Category : Fiction
Languages : en
Pages : 546

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Book Description
“Lean, taut storytelling . . . breakneck stuff . . . Arguably his most accessible book to date—Baxter [is] resplendent.”—SFX magazine When his father dies suddenly, George Poole stumbles onto a family secret: He has a twin sister he never knew existed, who was raised by an enigmatic cult called the Order. The Order is a hive—a human hive with a dominant queen—that has prospered below the streets of Rome for almost two millennia. After Poole enters the Order’s vast underground city and meets the disturbing inhabitants, he uncovers evidence that they have embarked on a divergent evolutionary path. These genetically superior humans are equipped with the tools necessary to render modern Homo sapiens as extinct as the Neanderthals. And now they are preparing to leave their underground realm. “[Excels] at both action-packed storytelling and philosophical speculation.”—Library Journal “Utterly fascinating . . . constantly surprising . . . Coalescent reveals a new side to Baxter’s vast talent.”—Locus

Gene Genealogies, Variation and Evolution: A primer in coalescent theory

Gene Genealogies, Variation and Evolution: A primer in coalescent theory PDF Author: Jotun Hein
Publisher: Oxford University Press, USA
ISBN: 9780191546150
Category : Population genetics
Languages : en
Pages : 298

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Book Description
Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)

Coalescent Theory

Coalescent Theory PDF Author: John Wakely
Publisher: Roberts
ISBN: 9780974707754
Category : Science
Languages : en
Pages : 0

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Book Description
This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.

Coalescent Argumentation

Coalescent Argumentation PDF Author: Michael A. Gilbert
Publisher: Routledge
ISBN: 1136685243
Category : Language Arts & Disciplines
Languages : en
Pages : 176

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Book Description
Coalescent Argumentation is based on the concept that arguments can function from agreement, rather than disagreement. To prove this idea, Gilbert first discusses how several components--emotional, visceral (physical) and kisceral (intuitive) are utilized in an argumentative setting by people everyday. These components, also characterized as "modes," are vital to argumentative communication because they affect both the argument and the resulting outcome. In addition to the components/modes, this book also stresses the goals in argumentation as a means for understanding one's own and one's opposer's positions. Gilbert argues that by viewing positions as complex human events involving a variety of communicative modes, we are better able to find commonalities across positions, and, therefore, move from conflict to resolution. By focusing on agreement and shared goals in all modes, arguers can coalesce diverse positions and more easily distinguish between minor or unrelated differences and core disagreements. This permits much greater latitude for locating shared beliefs, values, and attitudes that will lead to conflict resolution.

Dark Energy and Matter paths to continuous fusion through coalescent physics

Dark Energy and Matter paths to continuous fusion through coalescent physics PDF Author:
Publisher: Chris Zio
ISBN:
Category :
Languages : en
Pages : 104

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Book Description


Handbook of Statistical Genomics

Handbook of Statistical Genomics PDF Author: David J. Balding
Publisher: John Wiley & Sons
ISBN: 1119429250
Category : Science
Languages : en
Pages : 1828

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Book Description
A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Chiefdoms, Collapse, and Coalescence in the Early American South

Chiefdoms, Collapse, and Coalescence in the Early American South PDF Author: Robin Beck
Publisher: Cambridge University Press
ISBN: 1107355052
Category : History
Languages : en
Pages :

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Book Description
This book provides a new conceptual framework for understanding how the Indian nations of the early American South emerged from the ruins of a precolonial, Mississippian world. A broad regional synthesis that ranges over much of the Eastern Woodlands, its focus is on the Indians of the Carolina Piedmont - the Catawbas and their neighbors - from 1400 to 1725. Using an 'eventful' approach to social change, Robin Beck argues that the collapse of the Mississippian world was fundamentally a transformation of political economy, from one built on maize to one of guns, slaves and hides. The story takes us from first encounters through the rise of the Indian slave trade and the scourge of disease to the wars that shook the American South in the early 1700s. Yet the book's focus remains on the Catawbas, drawing on their experiences in a violent, unstable landscape to develop a comparative perspective on structural continuity and change.

Combinatorial Stochastic Processes

Combinatorial Stochastic Processes PDF Author: Jim Pitman
Publisher: Springer Science & Business Media
ISBN: 354030990X
Category : Mathematics
Languages : en
Pages : 257

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Book Description
The purpose of this text is to bring graduate students specializing in probability theory to current research topics at the interface of combinatorics and stochastic processes. There is particular focus on the theory of random combinatorial structures such as partitions, permutations, trees, forests, and mappings, and connections between the asymptotic theory of enumeration of such structures and the theory of stochastic processes like Brownian motion and Poisson processes.

Chiefdoms, Collapse, and Coalescence in the Early American South

Chiefdoms, Collapse, and Coalescence in the Early American South PDF Author: Robin Beck
Publisher: Cambridge University Press
ISBN: 1107022134
Category : History
Languages : en
Pages : 321

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Book Description
Offers a new framework for understanding the transformation of the Native American South during the first centuries of the colonial era.

Encyclopedia of Evolutionary Biology

Encyclopedia of Evolutionary Biology PDF Author:
Publisher: Academic Press
ISBN: 0128004266
Category : Science
Languages : en
Pages : 2138

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Book Description
Encyclopedia of Evolutionary Biology, Four Volume Set is the definitive go-to reference in the field of evolutionary biology. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic. The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature. While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Broad topics include the history of evolutionary biology, population genetics, quantitative genetics; speciation, life history evolution, evolution of sex and mating systems, evolutionary biogeography, evolutionary developmental biology, molecular and genome evolution, coevolution, phylogenetic methods, microbial evolution, diversification of plants and fungi, diversification of animals, and applied evolution. Presents fully comprehensive content, allowing easy access to fundamental information and links to primary research Contains concise articles by leading experts in the field that ensures current coverage of each topic Provides ancillary learning tools like tables, illustrations, and multimedia features to assist with the comprehension process