Animal Models in Eye Research PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Animal Models in Eye Research PDF full book. Access full book title Animal Models in Eye Research by . Download full books in PDF and EPUB format.
Author:
Publisher: Academic Press
ISBN: 9780080921037
Category : Science
Languages : en
Pages : 232
Get Book
Book Description
The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Author:
Publisher: Academic Press
ISBN: 9780080921037
Category : Science
Languages : en
Pages : 232
Get Book
Book Description
The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Author:
Publisher:
ISBN: 9814470392
Category :
Languages : en
Pages :
Get Book
Book Description
Author: Chi-Chao Chan
Publisher: Springer
ISBN: 3319194348
Category : Medical
Languages : en
Pages : 152
Get Book
Book Description
This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors. In conjunction, these models reflect the diversity and utility of tools used to study human disease. World expert clinicians discuss each model based on their clinical experience and the text is supported by numerous photos and diagrams. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents and medical students.
Author: P. Michael Conn
Publisher: Springer Science & Business Media
ISBN: 1597452858
Category : Medical
Languages : en
Pages : 756
Get Book
Book Description
The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.
Author: Andrzej Grzybowski
Publisher: Springer Nature
ISBN: 3030262693
Category : Medical
Languages : en
Pages : 560
Get Book
Book Description
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.
Author: Roger W. Beuerman
Publisher: World Scientific
ISBN: 981283298X
Category : Medical
Languages : en
Pages : 420
Get Book
Book Description
Section 1. Epidemiology and risk factors. ch. 1.1. Epidemiology of myopia and myopic shift in refraction / Barbara E.K. Klein. ch. 1.2. Environmental risk factors for myopia in children / Wilson C.J. Low, Tien-Yin Wong and Seang-Mei Saw. ch. 1.3. Gene-environment interactions in the aetiology of myopia / Ian G. Morgan and Kathryn A. Rose. ch. 1.4. The economics of myopia / Marcus C.C. Lim and Kevin D. Frick -- Section 2. Clinical studies and pathologic myopia. ch. 2.1. Quality of life and myopia / Ecosse L. Lamoureux and Hwee-Bee Wong. ch. 2.2. Ocular morbidity of pathological myopia / V. Swetha E. Jeganathan, Seang-Mei Saw and Tien-Yin Wong. ch. 2.3. Myopia and glaucoma / Shamira A. Perera and Tin Aung. ch. 2.4. The myopic retina / Shu-Yen Lee. ch. 2.5. Retinal function / Chi D. Luu and Audrey W.L. Chia -- Section 3. Genetics of myopia. ch. 3.1. New approaches in the genetics of myopia / Liang K. Goh, Ravikanth Metlapally and Terri Young. ch. 3.2. Twins studies and myopia / Maria Schäche and Paul N. Baird. ch. 3.3. TIGR, TGFB1, cMET, HGF, collagen genes, and myopia / Chiea-Chuen Khor. ch. 3.4. Statistical analysis of genome-wide association studies for myopia / Yi-Ju Li and Qiao Fan -- Section 4. Animal models and the biological basis of myopia. ch. 4.1. The relevance of studies in chicks for understanding myopia in humans / Josh Wallman and Debora L. Nickla. ch. 4.2. The mechanisms regulating scleral change in myopia / Neville A. McBrien. ch. 4.3. The mouse model of myopia / Frank Schaeffel. ch. 4.4. Gene analysis in experimental animal models of myopia / Roger W. Beuerman, Liang K. Goh and Veluchamy A. Barathi -- Section 5. Interventions for myopia. ch. 5.1. Atropine and other pharmacological approaches to prevent myopia / Louis M.G. Tong, Veluchamy A. Barathi and Roger W. Beuerman. ch. 5.2. Physical factors in myopia and potential therapies / Wallace S. Foulds and Chi D. Luu
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038391
Category : Science
Languages : en
Pages : 113
Get Book
Book Description
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author: Iok-Hou Pang
Publisher: Humana
ISBN: 9781493957507
Category : Medical
Languages : en
Pages : 229
Get Book
Book Description
Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal models for the prominent retinal diseases in order to aid in the evaluation, development, and improvement of therapeutic strategies. Beginning with an overview of the morphology of the retina, visual behavior, and genetics and genomics approaches for retinal research, the book continues by covering animal models for the research of specific human retinal diseases, e.g., retinal degeneration, age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, glaucoma, retinal ischemia, and retinal inflammation. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used approaches in the field. Vital and easy to use, Animal Models for Retinal Diseases serves to support the important future research of ocular investigators, ophthalmologists, and neuroscientists currently delving into this fascinating field of study.
Author: Joyce Tombran-Tink
Publisher: Springer Science & Business Media
ISBN: 159745186X
Category : Medical
Languages : en
Pages : 466
Get Book
Book Description
This book presents new and noteworthy research into retinal diseases. It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.
Author: Bahram Bodaghi
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805585842
Category : Anatomy
Languages : en
Pages : 0
Get Book
Book Description
A multidisciplinary and translational approach Doubtless, inflammatory processes are involved in the pathogenesis of various ocular diseases. Autoimmunity, inflammation and infection may initiate a large spectrum of pathologic processes or contribute to their progression. In light of the recent introduction of novel therapeutic interventions in ophthalmic disorders, it is necessary to revisit experimental models of ocular inflammation and discuss the relevance of each of them to human diseases. This publication presents the contributions made during the workshop on animal models of ocular inflammation held by the International Ocular Inflammation Society in Paris in 2007. The presence of expert immunologists, molecular biologists, geneticists and physicians, dealing with specific aspects of diseases, was a major step towards a multidisciplinary and translational approach. This special issue provides validated animal models addressing pathogenesis which are the starting point of developing novel therapies based on immune mechanisms learned from these models. Ophthalmologists, immunologists, pathologists and pharmacologists interested in drug delivery for intraocular disorders will find it valuable reading.
